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Article

Frequent deletions of JARID2 in leukemic transformation of chronic myeloid malignancies.

American journal of hematology - 1 Mar 2012

Puda Ana, Milosevic Jelena D, Berg Tiina, Klampfl Thorsten, Harutyunyan Ashot S, Gisslinger Bettina, Rumi Elisa, Pietra Daniela, Malcovati Luca, Elena Chiara, Doubek Michael, Steurer Michael, Tosic Natasa, Pavlovic Sonja, Guglielmelli Paola, Pieri Lisa, Vannucchi Alessandro M, Gisslinger Heinz, Cazzola Mario, Kralovics Robert

Abstract excerpt

Chronic myeloproliferative neoplasms (MPN) and myelodysplastic syndromes (MDS) have an inherent tendency to progress to acute myeloid leukemia (AML). Using high-resolution SNP microarrays, we studied a total of 517 MPN and MDS patients in different disease stages, including 77 AML cases with previous history of MPN (N = 46) or MDS (N = 31). Frequent chromosomal deletions of variable sizes were detected, allowing...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Enhancer of Zeste Homolog 2 Protein

Share to Leukemia, Myeloid

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Source

Identifiers

PMID: 22190018
DOI: 10.1002/ajh.22257

Genes

AEBP2
JARID2
SUZ12
ETV6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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