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Short communication: Screening of proof-of-concept mutations of honey bee acetylcholinesterase 2 conferring resistance to organophosphorus and carbamate insecticides.

Comparative biochemistry and physiology. Toxicology & pharmacology : CBP - 1 Feb 2023

Kim Sanghyeon, Yoon Kyungjae Andrew, Lee Si Hyeock

Abstract excerpt

The introduction of pesticide resistance-inducing mutations into target genes would in theory protect honey bees from the hazardous effects of pesticides. In this paper, to screen amino acid substitutions conferring resistance to organophosphorus and carbamate insecticides, honey bee acetylcholinesterase 2 (AmAChE2) variants with several mutations (V260L, A316S, G342A, G342V, F407Y, and G342V/F407Y) were...

Topics

Bees
Animals
Insecticides
Acetylcholinesterase
Pesticides
Mutation
Carbamates

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 36410640
DOI: 10.1016/j.cbpc.2022.109524

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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