Article
Identification and characterization of mutations in housefly (Musca domestica) acetylcholinesterase involved in insecticide resistance.
The Biochemical journal - 1 Oct 2001
Walsh S B, Dolden T A, Moores G D, Kristensen M, Lewis T, Devonshire A L, Williamson M S
Abstract excerpt
Acetylcholinesterase (AChE) insensitive to organophosphate and carbamate insecticides has been identified as a major resistance mechanism in numerous arthropod species. However, the associated genetic changes have been reported in the AChE genes from only three insect species; their role in conferring insecticide insensitivity has been confirmed, using functional expression, only for those in Drosophila...
Topics
- Acetylcholinesterase
- Amino Acid Substitution
- Animals
- Baculoviridae
- Carbamates
- Cholinesterase Inhibitors
- DNA Primers
- DNA, Complementary
- Drosophila melanogaster
- Genotype
- Houseflies
- Insecticide Resistance
- Insecticides