Article
Effects of mutations on the structure and function of silkworm type 1 acetylcholinesterase.
Pesticide biochemistry and physiology - 1 May 2016
Wang B B, Li F C, Xu K Z, Ni M, Hu J S, Tian J H, Li Y Y, Shen W D, Li B
Abstract excerpt
AChE is the target of organophosphate (OP) and carbamate (CB) pesticides, and mutations in the gene can significantly reduce insects' sensitivity to these pesticides. Bombyx mori is highly sensitive to pesticides. To investigate the effects of mutations on AChE1 structure and function, we used a prokaryotic system to express B.mori wild type AChE1 (wAChE1) and mutant AChE1 (mAChE1) in this study. Active AChE1...
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