Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Resistance-associated point mutations in insecticide-insensitive acetylcholinesterase.

21 Jun 1994

Abstract excerpt

Extensive utilization of pesticides against insects provides us with a good model for studying the adaptation of a eukaryotic genome to a strong selective pressure. One mechanism of resistance is the alteration of acetylcholinesterase (EC 3.1.1.7), the molecular target for organophosphates and carbamates. Here, we report the sequence analysis of the Ace gene in several resistant field strains of Drosophila...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cholinesterase and Neurodegenerative Diseases
Share to Computational Drug Discovery Methods
Share to Insect Resistance and Genetics

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 8016090
DOI: 10.1073/pnas.91.13.5922

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Resistance-associated point mutations in insecticide-insensitive acetylcholinesterase.PMID 8016090Read ↗

Mutations of acetylcholinesterase which confer insecticide resistance in Drosophila melanogaster populationsSemantic proximity Read ↗

Mutations of acetylcholinesterase which confer insecticide resistance in insect populations.Semantic proximity Read ↗

A High Number of Mutations in Insect Acetylcholinesterase May Provide Insecticide ResistanceSemantic proximity Read ↗

Organophosphosphate resistance‐related mutations in the acetylcholinesterase gene of TephritidaeSemantic proximity Read ↗

Mutation and duplication of arthropod acetylcholinesterase: Implications for pesticide resistance and tolerance.Semantic proximity Read ↗

Amino-acid substitutions in acetylcholinesterase 1 involved in insecticide resistance in mosquitoesSemantic proximity Read ↗

Acetylcholinesterase alterations reveal the fitness cost of mutations conferring insecticide resistance.Semantic proximity Read ↗

Insecticide resistance through mutations in cholinesterases or carboxylesterases: data mining in the ESTHER databaseSemantic proximity Read ↗

Amino acid substitutions conferring insecticide insensitivity in Ace-paralogous acetylcholinesteraseSemantic proximity Read ↗

Predicting the insecticide-driven mutations in a crop pest insect: Evidence for multiple polymorphisms of acetylcholinesterase gene with potential relevance for resistance to chemicals.Semantic proximity Read ↗

Why are there so few resistance-associated mutations in insecticide target genes?Semantic proximity Read ↗

A novel acetylcholinesterase gene in mosquitoes codes for the insecticide target and is non–homologous to the<i>ace</i>gene<i>Drosophila</i>Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.