Article
Evolutionary trade-offs of insecticide resistance - The fitness costs associated with target-site mutations in the nAChR of Drosophila melanogaster.
Molecular ecology - 1 Jul 2020
Homem Rafael A, Buttery Bliss, Richardson Ewan, Tan Yao, Field Linda M, Williamson Martin S, Emyr Davies T G
Abstract excerpt
The evolution of resistance to drugs and pesticides poses a major threat to human health and food security. Neonicotinoids are highly effective insecticides used to control agricultural pests. They target the insect nicotinic acetylcholine receptor and mutations of the receptor that confer resistance have been slow to develop, with only one field-evolved mutation being reported to date. This is an...
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