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Article

Molecular characterization of FLT3 mutations in acute leukemia patients in Pakistan.

Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2012

Ishfaq Mariam, Malik Arif, Faiz Mariam, Sheikh Ishfaq, Asif Muhammad, Khan Muhammad Nasrullah, Qureshi Muhammad Saeed, Zahid Sara, Manan Abdul, Arooj Mahwish, Qazi Mahmood Husain, Chaudhary Adeel, Alqahtani Mohammed Hussain, Rasool Mahmood

Abstract excerpt

Fms-like tyrosine kinase 3 (FLT3) performs a vital role in the pathogenesis of hematopoietic malignancies. Therefore in recent times, the focus of several studies was on use of FLT3 as a prognostic marker. The present study investigated the molecular characterization and incidence of FLT3 mutations in acute leukemia patients in Pakistan. A total of 55 patients were studied, of which 25 were suffering from acute...

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Identifiers

PMID: 23167384
DOI: 10.7314/apjcp.2012.13.9.4581

Genes

FLT3

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