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Nucleolar stress: Friend or foe in cardiac function?

31 Oct 2022

Abstract excerpt

Studies in the past decades have uncovered an emerging role of the nucleolus in stress response and human disease progression. The disruption of ribosome biogenesis in the nucleolus causes aberrant nucleolar architecture and function, termed nucleolar stress, to initiate stress-responsive pathways via nucleolar release sequestration of various proteins. While data obtained from both clinical and basic...

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PMID: 36386352
DOI: 10.3389/fcvm.2022.1045455

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