Article
Failing the four-gamete test enables exact phasing: the Corners' Algorithm.
Genetics, selection, evolution : GSE - 14 Nov 2022
Gomez-Raya Luis, Rauw Wendy M
Abstract excerpt
BACKGROUND: Failing the four-gamete test for two polymorphic DNA markers is an indication that two or three rather than four haplotypes segregate in the population. The objective of this paper is to show that when just three haplotypes are segregating, all three haplotypes can be fully and unambiguously phase-resolved. THEORY AND METHODS: The Corners' Algorithm tests the four corners in a 3 × 3 table of two-locus...
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