Article
Witch Nails (Krt90whnl): A spontaneous mouse mutation affecting nail growth and development.
PloS one - 1 Jan 2022
Sundberg John P, Galantino-Homer Hannah, Fairfield Heather, Ward-Bailey Patricia F, Harris Belinda S, Berry Melissa, Pratt C Herbert, Gott Nicholas E, Bechtold Lesley S, Kaplan Pauline R, Durbin-Johnson Blythe P, Rocke David M, Rice Robert H
Abstract excerpt
Numerous single gene mutations identified in humans and mice result in nail deformities with many similarities between the species. A spontaneous, autosomal, recessive mutation called witch nails (whnl) is described here where the distal nail matrix and nail bed undergo degenerative changes resulting in formation of an abnormal nail plate causing mice to develop long, curved nails. This mutation arose...
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