Article

Combined therapy of prednisone and mTOR inhibitor sirolimus for treating retroperitoneal fibrosis

2022-09-09

Abstract excerpt

Retroperitoneal fibrosis (RPF) is a rare autoimmune disease with fibrous tissue growth and inflammation in retroperitoneum, whose development could encase surrounding organs and lead to severe conditions. Its current treatments involve long-term uptake of glucocorticoids (e.g., prednisone) for controlling inflammation; however, side effects are common, triggering search for replacement therapies. Here, we surveyed...

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Literature Corpus work: c6fceb42-fe5d-5b1d-ac11-99935655b321
DOI: 10.1101/2022.09.05.22279516

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