Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The FADS1 rs174550 Genotype Modifies the n-3 and n-6 PUFA and Lipid Mediator Responses to a High Alpha-Linolenic Acid and High Linoleic Acid Diets.

Molecular nutrition & food research - 1 Dec 2022

Meuronen Topi, Lankinen Maria A, Kolmert Johan, de Mello Vanessa Derenji, Sallinen Taisa, Ågren Jyrki, Virtanen Kirsi A, Laakso Markku, Wheelock Craig E, Pihlajamäki Jussi, Schwab Ursula

Abstract excerpt

SCOPE: The fatty acid composition of plasma lipids, which is associated with biomarkers and risk of non-communicable diseases, is regulated by dietary polyunsaturated fatty acids (PUFAs) and variants of fatty acid desaturase (FADS). We investigated the interactions between dietary PUFAs and FADS1 rs174550 variant. METHODS AND RESULTS: Participants (n = 118), homozygous for FADS1 rs174550 variant (TT and CC)...

Read the complete abstract on PubMed

Topics

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share this publication in a Topic to start or enrich a Post.

Share to alpha-Linolenic Acid
Share to Diet
Share to Fatty Acid Desaturases
Share to Fatty Acids
Share to Fatty Acids, Unsaturated
Share to Genotype
Share to Linoleic Acid
Share to Polymorphism, Single Nucleotide

Source

Open in PubMed Open full text

Identifiers

PMID: 36367234
DOI: 10.1002/mnfr.202200351
PMCID: PMC10077898

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The FADS1 rs174550 Genotype Modifies the n-3 and n-6 PUFA and Lipid Mediator Responses to a High Alpha-Linolenic Acid and High Linoleic Acid Diets.PMID 36367234Read ↗

FADS1 rs174550 genotype and high linoleic acid diet modify plasma PUFA phospholipids in a dietary intervention study.Semantic proximity Read ↗

The FADS1 Genotype Modifies Metabolic Responses to the Linoleic Acid and Alpha-linolenic Acid Containing Plant Oils-Genotype Based Randomized Trial FADSDIET2.Semantic proximity Read ↗

Joint effects of fatty acid desaturase 1 polymorphisms and dietary polyunsaturated fatty acid intake on circulating fatty acid proportions.Semantic proximity Read ↗

The FADS1 genotypes modify the effect of linoleic acid-enriched diet on adipose tissue inflammation via pro-inflammatory eicosanoid metabolism.Semantic proximity Read ↗

Relationship between a common variant in the fatty acid desaturase (FADS) cluster and eicosanoid generation in humans.Semantic proximity Read ↗

Association between FADS1 rs174547 and levels of long-chain PUFA: a meta-analysis.Semantic proximity Read ↗

FADS2 polymorphisms are associated with plasma arachidonic acid and estimated desaturase-5 activity in a cross-sectional study.Semantic proximity Read ↗

Dietary n-3 and n-6 polyunsaturated fatty acid intake interacts with FADS1 genetic variation to affect total and HDL-cholesterol concentrations in the Doetinchem Cohort Study.Semantic proximity Read ↗

Dietary oils and FADS1-FADS2 genetic variants modulate [13C]α-linolenic acid metabolism and plasma fatty acid composition.Semantic proximity Read ↗

Dietary linoleic acid interacts with FADS1 genetic variability to modulate HDL-cholesterol and obesity-related traits.Semantic proximity Read ↗

Dietary n-3 alpha-linolenic and n-6 linoleic acids modestly lower serum lipoprotein(a) concentration but differentially influence other atherogenic lipoprotein traits: A randomized trial.Semantic proximity Read ↗

The impact of fatty acid desaturase genotype on fatty acid status and cardiovascular health in adults.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.