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Article

FADS1 rs174550 genotype and high linoleic acid diet modify plasma PUFA phospholipids in a dietary intervention study.

European journal of nutrition - 1 Mar 2022

Meuronen Topi, Lankinen Maria A, Kärkkäinen Olli, Laakso Markku, Pihlajamäki Jussi, Hanhineva Kati, Schwab Ursula

Abstract excerpt

INTRODUCTION: Fatty acid desaturase 1 (FADS1) gene encodes for delta-5 desaturase enzyme which is needed in conversion of linoleic acid (LA) to arachidonic acid (AA). Recent studies have shown that response to dietary PUFAs differs between the genotypes in circulating fatty acids. However, interactions between the FADS1 genotype and dietary LA on overall metabolism have not been studied. OBJECTIVES: We aimed to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34718859
DOI: 10.1007/s00394-021-02722-w
PMCID: PMC8854246

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