Article
Characteristics of BRCA2 Mutated Prostate Cancer at Presentation.
International journal of molecular sciences - 3 Nov 2022
Han Hyunho, Park Cheol Keun, Cho Nam Hoon, Lee Jongsoo, Jang Won Sik, Ham Won Sik, Choi Young Deuk, Cho Kang Su
Abstract excerpt
Genetic alterations of DNA repair genes, particularly BRCA2 in patients with prostate cancer, are associated with aggressive behavior of the disease. It has reached consensus that somatic and germline tests are necessary when treating advanced prostate cancer patients. Yet, it is unclear whether the mutations are associated with any presenting clinical features. We assessed the incidences and characteristics of...
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