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Somatic Tumor Testing in Prostate Cancer: Experience of a Tertiary Care Center Including Pathologist-Driven Reflex Testing of Localized Tumors at Diagnosis.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Jun 2024

Prendeville Susan, Kaur Harpreet, Ansari Shervin, Al Qa'qa' Shifaa', Stockley Tracy L, Lajkosz Katherine, van der Kwast Theodorus, Cheung Carol C, Selvarajah Shamini

Abstract excerpt

Somatic tumor testing in prostate cancer (PCa) can guide treatment options by identifying clinically actionable variants in DNA damage repair genes, including acquired variants not detected using germline testing alone. Guidelines currently recommend performing somatic tumor testing in metastatic PCa, whereas there is no consensus on the role of testing in regional disease, and the optimal testing strategy is...

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PMID: 38588883
DOI: 10.1016/j.modpat.2024.100489

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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