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Alterations in DNA Methylation in Orofacial Clefts

22 Oct 2022

Abstract excerpt

Orofacial clefts are among the most common craniofacial anomalies with multifactorial etiologies, including genetics and environments. DNA methylation, one of the most acknowledged mechanisms of epigenetics, is involved in the development of orofacial clefts. DNA methylation has been examined in patients with non-syndromic cleft lip with cleft palate (nsCL/P) from multiple specimens, including blood, saliva, lip,...

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PMID: 36361518
DOI: 10.3390/ijms232112727

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