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Article

Study on the role of methylation in nonsyndromic cleft lip with or without cleft palate using a monozygotic twin model.

International journal of pediatric otorhinolaryngology - 1 Apr 2021

Shi Xuheng, Wang Qi, Sun Changsheng, Guo Qiang, Song Tao

Abstract excerpt

OBJECTIVE: The research on the etiology of nonsyndromic cleft lip with or without cleft palate(NSCL/P) is challenging, and DNA methylation has an impact on the formation of cleft lip and palate. SUBJECTS: In this study, one of a pair of monozygotic twins (T1) had nonsyndromic cleft lip (NSCL), and one of a pair of monozygotic twins (T2) had nonsyndromic cleft lip and palate (NSCLP). We determined the methylation...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 33667834
DOI: 10.1016/j.ijporl.2021.110659

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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