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Article

Whole-genome sequencing of artificial single-nucleotide variants induced by DNA degradation in biological crime scene traces.

International journal of legal medicine - 1 Jan 2023

Schulze Johann Kristina, Bauer Hannah, Wiegand Peter, Pfeiffer Heidi, Vennemann Marielle

Abstract excerpt

The aim of this study was to identify artificial single-nucleotide variants (SNVs) in degraded trace DNA samples. In a preliminary study, blood samples were stored for up to 120 days and whole-genome sequencing was performed using the Snakemake workflow dna-seq-gatk-variant-calling to identify positions that vary between the time point 0 sample and the aged samples. In a follow-up study on blood and saliva...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 36352329
DOI: 10.1007/s00414-022-02911-0
PMCID: PMC9816238

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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