Article
Evaluation of mixed-source, low-template DNA profiles in forensic science.
Proceedings of the National Academy of Sciences of the United States of America - 23 Jul 2013
Balding David J
Abstract excerpt
Enhancements in sensitivity now allow DNA profiles to be obtained from only tens of picograms of DNA, corresponding to a few cells, even for samples subject to degradation from environmental exposure. However, low-template DNA (LTDNA) profiles are subject to stochastic effects, such as "dropout" and "dropin" of alleles, and highly variable stutter peak heights. Although the sensitivity of the newly developed...
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