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Performance of the ForenSeqTM DNA Signature Prep kit on highly degraded samples.

Electrophoresis - 1 Apr 2017

Fattorini Paolo, Previderé Carlo, Carboni Ilaria, Marrubini Giorgio, Sorçaburu-Cigliero Solange, Grignani Pierangela, Bertoglio Barbara, Vatta Paolo, Ricci Ugo

Abstract excerpt

Next generation sequencing (NGS) is the emerging technology in forensic genomics laboratories. It offers higher resolution to address most problems of human identification, greater efficiency and potential ability to interrogate very challenging forensic casework samples. In this study, a trial set of DNA samples was artificially degraded by progressive aqueous hydrolysis, and analyzed together with the...

Topics

DNA Fingerprinting
Electrophoresis, Capillary
Forensic Genetics
Genotype
Humans
Hydrolysis
Reagent Kits, Diagnostic
Reproducibility of Results
Sequence Analysis, DNA

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 28078776
DOI: 10.1002/elps.201600290

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