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Article

Preparing for Shotgun Sequencing in Forensic Genetics-A Workflow for Analysis of Monozygotic Twins.

Genes - 31 Mar 2026

Meyer Olivia Luxford, Børsting Claus, Andersen Jeppe Dyrberg, Kampmann Marie-Louise

Abstract excerpt

BACKGROUND/OBJECTIVES: Identifying the true perpetrator among monozygotic (MZ) twins has long posed a challenge in forensic genetics and for police investigations because MZ twins are likely identical in their short tandem repeat (STR) profile. In this study, we propose a workflow to address this issue, anchored in a case study involving MZ twins. METHODS: The workflow includes shotgun sequencing of reference...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 42074529
DOI: 10.3390/genes17040409
PMCID: PMC13116408

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