Article
Forensic genetic SNP typing of low-template DNA and highly degraded DNA from crime case samples.
Forensic science international. Genetics - 1 May 2013
Børsting Claus, Mogensen Helle Smidt, Morling Niels
Abstract excerpt
Heterozygote imbalances leading to allele drop-outs and disproportionally large stutters leading to allele drop-ins are known stochastic phenomena related to STR typing of low-template DNA (LtDNA). The large stutters and the many drop-ins in typical STR stutter positions are artifacts from the PCR amplification of tandem repeats. These artifacts may be avoided by typing bi-allelic markers instead of STRs. In this...
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