Article
Revealing the challenges of low template DNA analysis with the prototype Ion AmpliSeq™ Identity panel v2.3 on the PGM™ Sequencer.
Forensic science international. Genetics - 1 May 2016
Elena Salata, Alessandro Agostino, Ignazio Ciuna, Sharon Wootton, Luigi Ripani, Andrea Berti
Abstract excerpt
Forensic scientists frequently have to deal with the analysis of challenging sources of DNA such as degraded and low template DNA (LtDNA). The capacity to genotype difficult biological traces has been facilitated by emerging technologies. Massive parallel sequencing (MPS) on microchip among other technologies promises high sensitivity and discrimination power. In this study we evaluated the combined use of the...
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