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Prognostic impact of germline BRCA1/2 pathogenic variants in breast cancer.

Breast cancer research and treatment - 1 Jan 2023

Corso Giovanni, Girardi Antonia, Calvello Mariarosaria, Gandini Sara, Gaeta Aurora, Marabelli Monica, Magnoni Francesca, Veronesi Paolo, Guerrieri-Gonzaga Aliana, Bonanni Bernardo

Abstract excerpt

PURPOSE: This study investigates the impact of different subtypes of pathogenic BRCA variants on the prognosis and on the survival of breast cancer (BC) patients. METHODS: Associations between BRCA1/2 pathogenic variants (PVs) mutations, clinicopathological features, locoregional tumor reappearance, and survival data were analyzed. The Gray's test was used to test difference of the cumulative incidence of local...

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PMID: 36331686
DOI: 10.1007/s10549-022-06776-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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