Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Prognostic impact of BRCA1 pathogenic and BRCA1/BRCA2 unclassified variant mutations in patients with ovarian carcinoma.

Cancer - 1 Sept 2005

Majdak Ewa Joanna, Debniak Jaroslaw, Milczek Tomasz, Cornelisse Cees J, Devilee Peter, Emerich Janusz, Jassem Jacek, De Bock Geertruida Hendrika

Abstract excerpt

BACKGROUND: The clinical relevance of BRCA1/2 alterations in ovarian carcinoma patients is debatable. Our aim was to determine factors influencing the risk of recurrence and death in ovarian carcinoma patients with BRCA pathogenic and unclassified variant mutations. METHODS: A consecutive series of 205 women with primary ovarian carcinoma were screened for mutations in BRCA1 and BRCA2 genes using a conformational...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to BRCA2 gene

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genes, BRCA1

Share to Genes, BRCA2

Share to Mutation

Share to Neoplasm Recurrence, Local

Share to Ovarian Neoplasms

Share to Prognosis

Source

Identifiers

PMID: 16047333
DOI: 10.1002/cncr.21276

Genes

BRCA1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Prognostic impact of BRCA1 pathogenic and BRCA1/BRCA2 unclassified variant mutations in patients with ovarian carcinoma.PMID 16047333Read ↗

Clinical impact of unclassified variants of the BRCA1 and BRCA2 genes.Semantic proximity Read ↗

Prognostic impact of germline BRCA1/2 pathogenic variants in breast cancer.Semantic proximity Read ↗

BRCA1/BRCA2 Pathogenic Variant Breast Cancer: Treatment and Prevention Strategies.Semantic proximity Read ↗

BRCA1, BRCA2, and TP53 germline and somatic variants and clinicopathological characteristics of Brazilian patients with epithelial ovarian cancerSemantic proximity Read ↗

Frequency of germline mutations in BRCA1 and BRCA2 in ovarian cancer patients and their effect on treatment outcomeSemantic proximity Read ↗

Prediction of BRCA1/2 mutation status in patients with ovarian cancer from a hospital-based cohort.Semantic proximity Read ↗

BRCA1 and BRCA2 unclassified variants and missense polymorphisms in Algerian breast/ovarian cancer families.Semantic proximity Read ↗

Predicting ovarian/breast cancer pathogenic risks of BRCA1 gene variants of unknown significanceSemantic proximity Read ↗

Comparison of Clinical Outcomes of BRCA1/2 Pathologic Mutation, Variants of Unknown Significance, or Wild Type Epithelial Ovarian Cancer Patients.Semantic proximity Read ↗

Pathogenicity evaluation of BRCA1 and BRCA2 unclassified variants identified in Portuguese breast/ovarian cancer families.Semantic proximity Read ↗

Ovarian cancer pathology characteristics as predictors of variant pathogenicity in BRCA1 and BRCA2.Semantic proximity Read ↗

Patients with an unclassified genetic variant in the BRCA1 or BRCA2 genes show different clinical features from those with a mutation.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.