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Analysis of Pathogenic Variants in BRCA1 and BRCA2 Genes using Next-Generation Sequencing in Women with Triple Negative Breast Cancer from South India

2021-08-23

Abstract excerpt

<title>Abstract</title> <p>The frequency of triple-negative breast cancer (TNBC) incidence varies among different populations, suggesting the involvement of genetic component towards TNBC development. Previous studies have reported that <italic>BRCA1/2</italic> germline mutations confer a lifetime risk of developing TNBC. However, there is hardly any information regarding the common pathogenic variants (PVs) in <...

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Literature Corpus work
e45c6f98-54ce-5a33-a1c6-9d1c97c22d4d
DOI
10.21203/rs.3.rs-813826/v1
Open publication

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Analysis of Pathogenic Variants in BRCA1 and BRCA2 Genes using Next-Generation Sequencing in Women with Triple Negative Breast Cancer from South IndiaDOI 10.21203/rs.3.rs-813826/v1
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