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Article

BRCA1/BRCA2 Pathogenic Variant Breast Cancer: Treatment and Prevention Strategies.

Annals of laboratory medicine - 1 Mar 2020

Lee Anbok, Moon Byung In, Kim Tae Hyun

Abstract excerpt

Hereditary breast cancer is known for its strong tendency of inheritance. Most hereditary breast cancers are related to BRCA1/BRCA2 pathogenic variants. The lifelong risk of breast cancer in pathogenic BRCA1 and BRCA2 variant carriers is approximately 65% and 45%, respectively, whereas that of ovarian cancer is estimated to be 39% and 11%, respectively. Therefore, understanding these variants and clinical...

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Identifiers

PMID: 31650727
DOI: 10.3343/alm.2020.40.2.114
PMCID: PMC6822003

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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