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Clinical characteristics and prognostic analysis of acute myeloid leukemia patients with PTPN11 mutations.

Hematology (Amsterdam, Netherlands) - 1 Dec 2022

Sun Yueyue, Zhang Fenghong, Huo Li, Cai Wenzhi, Wang Qinrong, Wen Lijun, Yan Lingzhi, Shen Hongjie, Xu Xiaoyu, Chen Suning

Abstract excerpt

OBJECTIVES: Little is known about the clinical impact of germline/somatic mutations of PTPN11 in acute leukemia. The aim of this study was to investigate the clinical characteristics and prognostic impact of PTPN11 mutations in patients with acute myeloid leukemia (AML). METHODS: Seventy-four patients with PTPN11 mutation-positive AML treated at our institution were enrolled in this study. The prevalence of...

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Identifiers

PMID: 36318614
DOI: 10.1080/16078454.2022.2140274

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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