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[Clinical Characteristics and Prognostic Significance of PTPN11 Gene Mutations in Myelodysplastic Syndromes].

Zhongguo shi yan xue ye xue za zhi - 1 Dec 2024

Liu Jie, Chao Hong-Ying, Lu Xu-Zhang, Qin Wei, Li Jin, Xu Wei

Abstract excerpt

OBJECTIVE: To explore the mutation of PTPN11 gene in patients with myelodysplastic syndromes (MDS), and explore their correlation with mutations of other genes, clinical features and prognostic of patients. METHODS: High throughput DNA sequencing was used to identify mutations in common blood tumor genes. The mutational characteristics of the PTPN11 gene and the correlation between gene mutations and patients...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39743269
DOI: 10.19746/j.cnki.issn.1009-2137.2024.06.026

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