Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The clinical features and prognostic implications of PTPN11 mutation in adult patients with acute myeloid leukemia in China.

Cancer medicine - 1 Dec 2023

Yang Jinjun, Zhao Lei, Wu Yu, Niu Ting, Gong Yuping, Chen Xinchuan, Huang Xiaoou, Liu Jiazhuo, Dai Yang, Ma Hongbing

Abstract excerpt

BACKGROUND: The clinical significance of protein tyrosine phosphatase nonreceptor type 11 mutation (PTPN11mut ) in acute myeloid leukemia (AML) is underestimated. METHODS: We collected the data of AML patients with mutated PTPN11 and wild-type PTPN11 (PTPN11wt ) treated at our hospital and analyzed their clinical characteristics and prognosis. RESULTS: Fifty-nine PTPN11mut and 124 PTPN11wt AML patients were...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to China
Share to Leukemia, Myeloid, Acute

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mutation

Share to Nucleophosmin

Share to Prognosis

Share to Protein Tyrosine Phosphatase, Non-Receptor Type 11

Source

Open in PubMed Open full text

Identifiers

PMID: 37937729
DOI: 10.1002/cam4.6669
PMCID: PMC10726903

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The clinical features and prognostic implications of PTPN11 mutation in adult patients with acute myeloid leukemia in China.PMID 37937729Read ↗

Clinical characteristics and prognostic analysis of acute myeloid leukemia patients with PTPN11 mutations.Semantic proximity Read ↗

[Characteristic Analysis of Adult Acute Myeloid Leukemia Patients with PTPN11 Gene Mutation].Semantic proximity Read ↗

The Clinical impact of PTPN11 mutations in adults with acute myeloid leukemia.Semantic proximity Read ↗

Impact of PTPN11 mutations on clinical outcome analyzed in 1529 patients with acute myeloid leukemia.Semantic proximity Read ↗

Molecular, clinical, and prognostic implications of PTPN11 mutations in acute myeloid leukemia.Semantic proximity Read ↗

PTPN11 mutations in adult acute myeloid leukaemia: Prevalence and clinical implications in the context of NPM1 mutation.Semantic proximity Read ↗

[Clinical Characteristics and Prognostic Significance of PTPN11 Gene Mutations in Myelodysplastic Syndromes].Semantic proximity Read ↗

Pan-cancer analysis revealing that PTPN2 is a indicator of risk stratification for acute myeloid leukemia identification of high-risk patientsSemantic proximity Read ↗

Comprehensive analysis of PTPN family expression and prognosis in acute myeloid leukemiaSemantic proximity Read ↗

PTPN11 mutations in pediatric patients with acute myeloid leukemia: results from the Children's Cancer GroupSemantic proximity Read ↗

SETBP-1 mutations favor transformation to AML in PTPN-11 positive JMMLSemantic proximity Read ↗

Acute myeloid leukemia in an adult Noonan syndrome patient with PTPN11 mutation.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.