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Article

Transcriptional factor III A promotes colorectal cancer progression by upregulating cystatin A

13 Oct 2022

Abstract excerpt

BACKGROUND: Advanced colorectal cancer (CRC) generally has poor outcomes and high mortality rates. Clarifying the molecular mechanisms underlying CRC progression is necessary to develop new diagnostic and therapeutic strategies to improve CRC outcome and decrease mortality. Transcriptional factor III A (GTF3A), an RNA polymerase III transcriptional factor, is a critical driver of tumorgenesis and aggravates CRC...

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PMID: 36310710
DOI: 10.4251/wjgo.v14.i10.1918

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