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POLE2 silencing inhibits the progression of colorectal carcinoma cells via wnt signaling axis

18 Aug 2024

Abstract excerpt

Colorectal cancer (CRC) is one of the most common malignant carcinoma worldwide. DNA polymerase epsilon 2, accessory subunit (POLE2) participates in DNA replication, repair, and cell cycle control, but its association with CRC development remains unclear. In the present study, the differentially expressed genes (DEGs) in CRC were screened from bioinformatics analysis based on GEO database. RT-qPCR was used to...

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PMID: 39155507
DOI: 10.1080/15384047.2024.2392339

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