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Emerging Functions of Human IFIT Proteins in Cancer

18 Dec 2019

Abstract excerpt

. The expression of IFIT genes is very low in most cell types, whereas their expression is greatly enhanced by interferon treatment, viral infection, and pathogen-associated molecular patterns (PAMPs). The proteins encoded by IFIT genes have multiple tetratricopeptide repeat (TPR) motifs. IFIT proteins do not have any known enzymatic roles. However, they execute a variety of cellular functions by mediating...

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Cytokine Signaling Pathways and Interactions
interferon and immune responses
RNA modifications and cancer

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 31921891
DOI: 10.3389/fmolb.2019.00148

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