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Article

Prognostic Role of DNA Damage Response Genes Mutations and their Association With the Sensitivity of Olaparib in Prostate Cancer Patients.

Cancer control : journal of the Moffitt Cancer Center - 1 Jan 2000

Zhang Dong, Xu Xinchi, Wei Yuang, Chen Xinglin, Li Guangyao, Lu Zhongwen, Zhang Xu, Ren Xiaohan, Wang Shangqian, Qin Chao

Abstract excerpt

OBJECTIVE: Evidence shows that gene mutation is a significant proportion of genetic factors associated with prostate cancer. The DNA damage response (DDR) is a signal cascade network that aims to maintain genomic integrity in cells. This comprehensive study was performed to determine the link between different DNA damage response gene mutations and prostate cancer. MATERIALS AND METHODS: A systematic literature...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 36283420
DOI: 10.1177/10732748221129451
PMCID: PMC9608002

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