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Article

Identification of DNA Damage Repair-Associated Prognostic Biomarkers for Prostate Cancer Using Transcriptomic Data Analysis.

International journal of molecular sciences - 29 Oct 2021

Teng Pai-Chi, Huang Shu-Pin, Liu Chia-Hsin, Lin Ting-Yi, Cho Yi-Chun, Lai Yo-Liang, Wang Shu-Chi, Yeh Hsin-Chih, Chuu Chih-Pin, Chen Deng-Neng, Cheng Wei-Chung, Li Chia-Yang

Abstract excerpt

In the recent decade, the importance of DNA damage repair (DDR) and its clinical application have been firmly recognized in prostate cancer (PC). For example, olaparib was just approved in May 2020 to treat metastatic castration-resistant PC with homologous recombination repair-mutated genes; however, not all patients can benefit from olaparib, and the treatment response depends on patient-specific mutations....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34769200
DOI: 10.3390/ijms222111771
PMCID: PMC8584064

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