Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Dog ownership in infancy is protective for persistent wheeze in 17q21 asthma-risk carriers

20 Oct 2022

Abstract excerpt

Background Asthma-associated single nucleotide polymorphisms from large genome-wide association studies only explain a fraction of genetic heritability. Likely causes of the missing heritability include broad phenotype definitions and gene-environment interactions (GxE). The mechanisms underlying GxE in asthma are poorly understood. Previous GxE studies on pet ownership showed discordant results. Objectives We...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Asthma and respiratory diseases
Share to Human-Animal Interaction Studies
Share to Veterinary Oncology Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 36273658
DOI: 10.1016/j.jaci.2022.10.012

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Dog ownership in infancy is protective for persistent wheeze in 17q21 asthma-risk carriersPMID 36273658Read ↗

Cat exposure in early life decreases asthma risk from the 17q21 high-risk variant.Semantic proximity Read ↗

The Early Development of Wheeze. Environmental Determinants and Genetic Susceptibility at 17q21.Semantic proximity Read ↗

17q12-21 and asthma: interactions with early-life environmental exposures.Semantic proximity Read ↗

Effects of dog ownership and genotype on immune development and atopy in infancy.Semantic proximity Read ↗

Interactions with early-life exposures modulate polygenic risk of wheeze and asthma in preschool-aged childrenSemantic proximity Read ↗

Chromosome 17q21 gene variants are associated with asthma and exacerbations but not atopy in early childhood.Semantic proximity Read ↗

Effects of a 17q21 chromosome gene variant, tobacco smoke and furred pets on infant wheeze.Semantic proximity Read ↗

Gene-Environment Interaction Affects Risk of Atopic Eczema: Population and In Vitro Studies.Semantic proximity Read ↗

Gene-environment interaction analysis in atopic eczema: evidence from large population datasets and modelling <i>in vitro</i>Semantic proximity Read ↗

Genetics of preschool wheeze and its progression to childhood asthma.Semantic proximity Read ↗

Opposing effects of cat and dog ownership and allergic sensitization on eczema in an atopic birth cohort.Semantic proximity Read ↗

Genetic characterization of preschool wheeze phenotypes.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.