Article
Association Between Systemic Lupus Erythematosus and Primary Hypothyroidism: Evidence from Complementary Genetic Methods.
The Journal of clinical endocrinology and metabolism - 10 Mar 2023
Liu Xue, Yuan Jie, Zhou Huizhi, Wang Yuyao, Tian Guoyu, Liu Xueying, Wang Xinhui, Tang Mulin, Meng Xue, Kou Chunjia, Yang Qingqing, Li Juyi, Zhang Li, Ji Jiadong, Zhang Haiqing
Abstract excerpt
INTRODUCTION: Systemic lupus erythematosus (SLE) and hypothyroidism often coexist in observational studies; however, the causal relationship between them remains controversial. METHODS: Complementary genetic approaches, including genetic correlation, Mendelian randomization (MR), and colocalization analysis, were conducted to assess the potential causal association between SLE and primary hypothyroidism using...
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