Rheumatoid arthritis and hypothyroidism: a bidirectional Mendelian randomization study

Abstract excerpt

Object Though significant correlations between rheumatoid arthritis (RA) and hypothyroidism have been found in earlier observational studies, their underlying causal relationship is still unknown. Mendelian randomization (MR) was used in the current study to assess the bidirectional causation between RA and hypothyroidism. Method We gathered summary data from genome-wide association studies (GWASs) of RA and...

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