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MgrB Mutations and Altered Cell Permeability in Colistin Resistance in Klebsiella pneumoniae.

Cells - 26 Sept 2022

Yap Polly Soo-Xi, Cheng Wan-Hee, Chang Sook-Keng, Lim Swee-Hua Erin, Lai Kok-Song

Abstract excerpt

There has been a resurgence in the clinical use of polymyxin antibiotics such as colistin due to the limited treatment options for infections caused by carbapenem-resistant Enterobacterales (CRE). However, this last-resort antibiotic is currently confronted with challenges which include the emergence of chromosomal and plasmid-borne colistin resistance. Colistin resistance in Klebsiella pneumoniae is commonly...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 36230959
DOI: 10.3390/cells11192995
PMCID: PMC9564205

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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