Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Organic Anion Transporters (OAT) and Other SLC22 Transporters in Progression of Renal Cell Carcinoma

29 Sept 2022

Abstract excerpt

(1) Background: Many transporters of the SLC22 family (e.g., OAT1, OAT3, OCT2, URAT1, and OCTN2) are highly expressed in the kidney. They transport drugs, metabolites, signaling molecules, antioxidants, nutrients, and gut microbiome products. According to the Remote Sensing and Signaling Theory, SLC22 transporters play a critical role in small molecule communication between organelles, cells and organs as well as...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Enzymes and Metabolism
Share to Drug Transport and Resistance Mechanisms
Share to Epigenetics and DNA Methylation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 36230695
DOI: 10.3390/cancers14194772

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Organic Anion Transporters (OAT) and Other SLC22 Transporters in Progression of Renal Cell CarcinomaPMID 36230695Read ↗

Systems Biology Analysis Reveals Eight SLC22 Transporter Subgroups, Including OATs, OCTs, and OCTNs.Semantic proximity Read ↗

Analysis of ABCG2 and other urate transporters in uric acid homeostasis in chronic kidney disease: potential role of remote sensing and signalingSemantic proximity Read ↗

Evolutionary Analysis and Classification of OATs, OCTs, OCTNs, and Other SLC22 Transporters: Structure-Function Implications and Analysis of Sequence Motifs.Semantic proximity Read ↗

The SLC Family Are Candidate Diagnostic and Prognostic Biomarkers in Clear Cell Renal Cell CarcinomaSemantic proximity Read ↗

Handling of Drugs, Metabolites, and Uremic Toxins by Kidney Proximal Tubule Drug TransportersSemantic proximity Read ↗

Genetic Heterogeneity of SLC22 Family of Transporters in Drug DispositionSemantic proximity Read ↗

SLC22 Transporters in the Fly Renal System Regulate Response to Oxidative Stress In VivoSemantic proximity Read ↗

Unraveling the functional role of the orphan solute carrier, SLC22A24 in the transport of steroid conjugates through metabolomic and genome-wide association studiesSemantic proximity Read ↗

Unraveling the functional role of the orphan solute carrier, SLC22A24 in the transport of steroid conjugates through metabolomic and genome-wide association studiesSemantic proximity Read ↗

Hyperuricemia and Diabetic Kidney Disease: A Mechanistic Exploration and Clinical Translation Study Based on Multi-Omics Integration and Real-World EvidenceSemantic proximity Read ↗

Novel slc22 transporter homologs in fly, worm, and human clarify the phylogeny of organic anion and cation transportersSemantic proximity Read ↗

DNA methylation is associated with downregulation of the organic cation transporter OCT1 (SLC22A1) in human hepatocellular carcinomaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.