Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Analysis of ABCG2 and other urate transporters in uric acid homeostasis in chronic kidney disease: potential role of remote sensing and signaling

5 Apr 2016

Abstract excerpt

BACKGROUND: In the setting of chronic kidney disease (CKD), altered extra-renal urate handling may be necessary to regulate plasma uric acid. The Remote Sensing and Signaling Hypothesis (Nigam S. What do drug transporters really do? Nat Rev Drug Discov 2015; 14: 29-44) suggests that multispecific solute carrier (SLC) and ATP-binding cassette (ABC) drug transporters in different tissues are part of an inter-organ...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Drug Transport and Resistance Mechanisms
Share to Gout, Hyperuricemia, Uric Acid
Share to Kidney Stones and Urolithiasis Treatments

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 27274832
DOI: 10.1093/ckj/sfw010

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Analysis of ABCG2 and other urate transporters in uric acid homeostasis in chronic kidney disease: potential role of remote sensing and signalingPMID 27274832Read ↗

Organic Anion Transporters (OAT) and Other SLC22 Transporters in Progression of Renal Cell CarcinomaSemantic proximity Read ↗

The Role of ABCG2 in the Pathogenesis of Primary Hyperuricemia and Gout-An Update.Semantic proximity Read ↗

Recent advances in renal urate transport: characterization of candidate transporters indicated by genome-wide association studies.Semantic proximity Read ↗

Hyperuricemia and its related diseases: mechanisms and advances in therapySemantic proximity Read ↗

A 'complexity' of urate transporters.Semantic proximity Read ↗

Genetics of serum urate concentrations and gout in a high-risk population, patients with chronic kidney disease.Semantic proximity Read ↗

ABCG2 as a therapeutic target candidate for gout.Semantic proximity Read ↗

The Epidemiology and Genetics of Hyperuricemia and Gout across Major Racial Groups: A Literature Review and Population Genetics Secondary Database AnalysisSemantic proximity Read ↗

The Epidemiology and Genetics of Hyperuricemia and Gout Across Major Racial Groups: A literature Review and Population Genetics Secondary Data AnalysisSemantic proximity Read ↗

SLC2A9 is a newly identified urate transporter influencing serum urate concentration, urate excretion and gout.Semantic proximity Read ↗

[Urate transporter and renal hypouricemia].Semantic proximity Read ↗

Identification of a urate transporter, ABCG2, with a common functional polymorphism causing gout.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.