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SLC22 Transporters in the Fly Renal System Regulate Response to Oxidative Stress In Vivo

14 Dec 2021

Abstract excerpt

Several SLC22 transporters in the human kidney and other tissues are thought to regulate endogenous small antioxidant molecules such as uric acid, ergothioneine, carnitine, and carnitine derivatives. These transporters include those from the organic anion transporter (OAT), OCTN/OCTN-related, and organic cation transporter (OCT) subgroups. In mammals, it has been difficult to show a clear in vivo role for these...

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PMID: 34948211
DOI: 10.3390/ijms222413407

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