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Article

An updated counseling framework for moderate-penetrance colorectal cancer susceptibility genes.

Genetics in medicine : official journal of the American College of Medical Genetics - 1 Dec 2022

Breen Kelsey E, Katona Bryson W, Catchings Amanda, Ranganathan Megha, Marcell Vanessa, Latham Alicia, Yurgelun Matthew B, Stadler Zsofia K

Abstract excerpt

PURPOSE: With the recent guideline change for individuals at average risk for colorectal cancer (CRC) to initiate colonoscopy at the age of 45 years, there is a need to provide an updated counseling framework for individuals with variants in moderate-penetrance CRC susceptibility genes. METHODS: Population age-specific incidence rates for CRC were obtained from the 2014-2018 US Surveillance, Epidemiology, and End...

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Identifiers

PMID: 36222830
DOI: 10.1016/j.gim.2022.08.027

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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