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Article

Universal germline testing among patients with colorectal cancer: clinical actionability and optimised panel.

Journal of medical genetics - 1 Apr 2022

Jiang Wu, Li Lin, Ke Chuan-Feng, Wang Wei, Xiao Bin-Yi, Kong Ling-Heng, Tang Jing-Hua, Li Yuan, Wu Xiao-Dan, Hu Ying, Guo Wei-Hua, Wang Si-Zhen, Wan De-Sen, Xu Rui-Hua, Pan Zhi-Zhong, Ding Pei-Rong

Abstract excerpt

PURPOSE: Universal germline testing in patients with colorectal cancer (CRC) with a multigene panel can detect various hereditary cancer syndromes. This study was performed to understand how to choose a testing panel and whether the result would affect clinical management. METHODS: We prospectively enrolled 486 eligible patients with CRC, including all patients with CRC diagnosed under age 70 years and patients...

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Source

Identifiers

PMID: 33563768
DOI: 10.1136/jmedgenet-2020-107230

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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