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Article

Phenotypic Characterization and Isolation of Myeloid-Derived Suppressor Cells.

Current protocols - 1 Oct 2022

Reuven Or, Mikula Ivan, Ashkenazi-Preiser Hadas, Twaik Nira, Ben-Meir Kerem, Meirow Yaron, Daniel Leonor, Kariv Guy, Kurd Mahdi, Baniyash Michal

Abstract excerpt

Myeloid-derived suppressor cells (MDSCs) are heterogenous populations of immature myeloid cells that can be divided into two main subpopulations, polymorphonuclear (PMN) MDSCs and monocytic (M) MDSCs. These cells accumulate during chronic inflammation and induce immunosuppression evident in an array of pathologies such as cancer, inflammatory bowel disease, and infectious and autoimmune diseases. Herein, we...

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PMID: 36214619
DOI: 10.1002/cpz1.561
PMCID: PMC11648828

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