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Phenotypical Characterization and Isolation of Tumor-Derived Mouse Myeloid-Derived Suppressor Cells.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2021

Barouni Roza Maria, Musiu Chiara, Bronte Vincenzo, Ugel Stefano, Canè Stefania

Abstract excerpt

Myeloid-derived suppressor cells (MDSCs) are a heterogeneous cell population composed of mature and immature cells of myeloid origin that play a major role in tumor progression by inhibiting the antitumor immune responses mediated by T cells. In this chapter, we describe protocols for isolation, phenotypical and functional evaluation of MDSCs isolated from mouse tumors, with the aim at unifying and standardizing...

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PMID: 33237538
DOI: 10.1007/978-1-0716-1060-2_4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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