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Article

Homocysteine, folate, and nonalcoholic fatty liver disease: a systematic review with meta-analysis and Mendelian randomization investigation.

The American journal of clinical nutrition - 19 Dec 2022

Yuan Shuai, Chen Jie, Dan Lintao, Xie Ying, Sun Yuhao, Li Xue, Larsson Susanna C

Abstract excerpt

BACKGROUND: Circulating concentrations of homocysteine and folate are inconsistently associated with the risk of nonalcoholic fatty liver disease (NAFLD) in observational studies. OBJECTIVES: We conducted a meta-analysis and Mendelian randomization (MR) analyses to examine these associations. METHODS: We performed a meta-analysis of observational studies identified from 3 databases to evaluate the associations of...

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Identifiers

PMID: 36205540
DOI: 10.1093/ajcn/nqac285

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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