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Iron status and non-alcoholic fatty liver disease: A Mendelian randomization study.

Nutrition (Burbank, Los Angeles County, Calif.) - 1 Feb 2024

Sun Kexin, Zhao Jie V, Nelson Edmund Anthony Severn, Wong Vincent Wai Sun, Lam Hugh Simon Hung San, Hui Lai Ling

Abstract excerpt

OBJECTIVES: The aim of this study was to assess the association of genetically determined iron status with the risk for non-alcoholic fatty liver disease (NAFLD) using two-sample Mendelian randomization (MR) analysis. METHODS: We applied single nucleotide polymorphisms (SNPs) associated at genome-wide significance with iron status proxied by serum iron, ferritin, transferrin, and transferrin saturation from the...

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PMID: 38103266
DOI: 10.1016/j.nut.2023.112295

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