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Article

Associations between Methylenetetrahydrofolate Reductase (MTHFR) Polymorphisms and Non-Alcoholic Fatty Liver Disease (NAFLD) Risk: A Meta-Analysis.

PloS one - 1 Jan 2016

Sun Man-Yi, Zhang Li, Shi Song-Li, Lin Jing-Na

Abstract excerpt

BACKGROUND: C677T and A1298C are the most common allelic variants of Methylenetetrahydrofolate Reductase (MTHFR) gene. The association between MTHFR polymorphisms and the occurrence of non-alcoholic fatty liver disease (NAFLD) remains controversial. This study was thus performed to examine whether MTHFR mutations are associated with the susceptibility to NAFLD. METHODS: A first meta-analysis on the association...

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Identifiers

PMID: 27128842
DOI: 10.1371/journal.pone.0154337
PMCID: PMC4851382

Genes

MTHFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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