Article
Lifestyle and metabolic factors for nonalcoholic fatty liver disease: Mendelian randomization study.
European journal of epidemiology - 1 Jul 2022
Yuan Shuai, Chen Jie, Li Xue, Fan Rongrong, Arsenault Benoit, Gill Dipender, Giovannucci Edward L, Zheng Ju-Sheng, Larsson Susanna C
Abstract excerpt
The risk factors for nonalcoholic fatty liver disease (NAFLD) have not been clearly identified. We conducted a Mendelian randomization (MR) study to explore this. Independent genetic variants strongly associated with 5 lifestyle and 9 metabolic factors were selected as instrumental variables from corresponding genome-wide association studies (GWASs). Summary-level data for NAFLD were obtained from a GWAS...
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